Publications

  1. Klusmann JH, Godinho FJ, Heitmann K, Maroz A, Koch ML, Reinhardt D, Orkin SH, Li Z. Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis. Genes Dev. 2010;24:1659-1672.
  2. Klusmann JH, Li Z, Bohmer K, Maroz A, Koch ML, Emmrich S, Godinho FJ, Orkin SH, Reinhardt D. miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia. Genes Dev. 2010;24:478-490.
  3. Klusmann JH, Creutzig U, Zimmermann M, Dworzak M, Jorch N, Langebrake C, Pekrun A, Macakova-Reinhardt K, Reinhardt D. Treatment and prognostic impact of transient leukemia in neonates with Down syndrome. Blood 2008;111:2991-2998.
  4. Klusmann JH, Reinhardt D, Hasle H, Kaspers GJ, Creutzig U, Hahlen K, van den Heuvel-Eibrink MM, Zwaan CM. Janus kinase mutations in the development of acute megakaryoblastic leukemia in children with and without Down's syndrome. Leukemia 2007;21:1584-1587.
  5. Langebrake CWK*, Klusmann JH*, Kolar M, Puhlmann U, Reinhardt D. Concomitant aberrant overexpression of RUNX1 and NCAM in regenerating bone marrow of myeloid leukemia of Down's syndrome. Haematologica 2006;91:1473-1480. *contributed equally.
  6. Li Z, Godinho FJ, Klusmann JH, Garriga-Canut M, Yu C, Orkin SH. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat.Genet. 2005;37:613-619.
  7. Ehlers S, Herbst C, Zimmermann M, Scharn N, Germeshausen M, von Neuhoff N, Zwaan CM, Reinhardt K, Hollink IH, Klusmann JH, Lehrnbecher T, Roettgers S, Stary J, Dworzak M, Welte K, Creutzig U, Reinhardt D. Granulocyte Colony-Stimulating Factor (G-CSF) Treatment of Childhood Acute Myeloid Leukemias That Overexpress the Differentiation-Defective G-CSF Receptor Isoform IV Is Associated With a Higher Incidence of Relapse. J.Clin.Oncol. 2010;28:2591-2597.
  8. Emmrich S, Pützer BM. Checks and balances: E2F-microRNA crosstalk in cancer control. Cell Cycle. 2010 Jul 14;9(13):2553-65.
  9. Emmrich S, Wang W, John K, Li W, Pützer BM. Antisense Gapmers selectively suppress individual oncogenic p73 splice isoforms and inhibit tumor growth in vivo. Mol Cancer. 2009 Aug 11;8:61.
  10. Winzen R*, Thakur BK*, Breiholz O, Shah M, Redich N, Dhamija S, Kracht M and Holtmann H. Functional analysis of KSRP interaction with the AU-rich element of IL‑8 and identification of inflammatory mRNA targets. Mol Cell Biol, 27(23), 8388, Dec 2007. *contributed equally.
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